45 Results for "

Erythrina sigmoidea Hua

" in MedChemExpress (MCE) Product Catalog:
Products (45)

45 Results for "Erythrina sigmoidea Hua" in MCE Product Catalog:

2
Wighteone
Wighteone
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2 Cited Publications
Cat. No.: HY-N1073
CAS No.: 51225-30-0
Synonyms: 6-Isopentenylgenistein; Erythrinin B
Category:  

Leguminosae Genista ephedroides DC. Plants Isoflavones

Target:  

Apoptosis EGFR HSP ERK Akt

Wighteone (6-Isopentenylgenistein; Erythrinin B) is a prenylated isoflavone that acts as a HSP90/EGFR L858R/T790M inhibitor and antifungal agent. Wighteone reduces the expression level of HSP90, blocks EGF-induced phosphorylation of EGFR, and thereby inhibits the downstream ERK and AKT signaling pathways. Wighteone induces cell cycle redistribution, inhibits proliferation and triggers apoptosis in cancer cells. Wighteone can be isolated from Erythrina suberosa, and can also be induced to synthesize in Lotus japonicus under specific conditions. Wighteone can be used to study HER2-positive breast cancer, leukemia, non-small cell lung cancer with EGFR L858R/T790M mutation, and fungal infections .
1
Dihydro-β-erythroidine hydrobromide
Dihydro-β-erythroidine hydrobromide
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1 Cited Publications
Cat. No.: HY-107670
CAS No.: 29734-68-7
Purity:  98.85%
Synonyms: DHβE hydrobromide
Category:  

Alkaloids Piperidine Alkaloids Leguminosae Plants Erythrina

Target:  

nAChR

Dihydro-β-erythroidine (DHβE) hydrobromide is a potent, orally active, and competitive antagonist of neuronal nAChRs. Dihydro-β-erythroidine hydrobromide shows selectivity for α4β4 and α4β2 nAChRs, with IC50s of 0.19 and 0.37 μM, respectively. Antidepressant-like activities .
1
Praeruptorin C
Praeruptorin C
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1 Cited Publications
Cat. No.: HY-N0079
CAS No.: 72463-77-5
Category:  

Cardiovascular Disease Chrysanthemum × morifolium (Ramat.) Hemsl. Coumarins Phenylpropanoids Plants Umbelliferae Disease Research Fields

Target:  

Calcium Channel

Praeruptorin C is a main bioactive constituent of Peucedanum praeruptorum (also known as Bai-Hua Qian Hu). Praeruptorin C is a calcium antagonist with pD2 ′ value of 5.7 .
1
Erythrinin C
Erythrinin C
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1 Cited Publications
Cat. No.: HY-N3857
CAS No.: 63807-85-2
Category:  

Flavonoids Leguminosae Erythrina suberosa Roxb. Plants Isoflavones

Target:  

Others

Erythrinin C is an isoflavones that can be isolated from Erythrina suberosa var .
2,3-Dehydrokievitone
2,3-Dehydrokievitone
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Cat. No.: HY-N1653
CAS No.: 74161-25-4
Category:  

Flavonoids Leguminosae Other Diseases Maackia taiwanensis Hoshi & H. Ohashi Phenols Polyphenols Plants Disease Research Fields Isoflavones

Target:  

Others

2,3-Dehydrokievitone is a isoflavanone found in Erythrina sacleuxii .
Kihadanin A
Kihadanin A
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Cat. No.: HY-N8761
CAS No.: 125276-62-2
Category:  

Natural Products Dictamnus dasycarpus Turcz. Rutaceae Plants

Target:  

NO Synthase

Kihadanin A (compound 3) is a limonoid NOS3 inhibitor that can be isolated from the methanol extract of Dictamnus dasycarpus root bark. Kihadanin A is useful in the study of hyperuricemia (HUA) [3].
Limonianin
Limonianin
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Cat. No.: HY-N2906
CAS No.: 119309-02-3
Synonyms: Atalantoflavone
Category:  

Flavonoids Flavones Rutaceae Atalantia buxifolia (Poir.) Oliv. Plants

Target:  

Parasite

Limonianin (Atalantoflavone) is a flavone, that can be isolated from Erythrina sigmoidea and the root bark of Citrus limonia. Limonianin presents inhibitory effect against P. gingivalis. Limonianin shows cytotoxic activity against multidrug-resistant (MDR) cancer cell lines .
Isoerysenegalensein E
Isoerysenegalensein E
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Cat. No.: HY-N3484
CAS No.: 478158-77-9
Category:  

Erythrina lysistemon Hutch. Flavonoids Leguminosae Plants Isoflavones

Target:  

Others

Isoerysenegalensein E (compound 3) is a natural product that can be found in Erythrina lysistemon .
Alpinumisoflavone
Alpinumisoflavone
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Cat. No.: HY-N2857
CAS No.: 34086-50-5
Category:  

Flavonoids Leguminosae Other Diseases Phenols Polyphenols Plants Disease Research Fields Erythrina variegata Linn. Isoflavones

Target:  

Others

Alpinumisoflavone (compound 2) is a flavonoid derivative isolated from the stem bark of Erythrina lysistemon Hutch .
NLRP3/URAT1-IN-1
NLRP3/URAT1-IN-1
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Cat. No.: HY-175645
CAS No.: 2994637-53-3
Target:  

NOD-like Receptor (NLR) URAT1 Interleukin Related OAT GLUT

Research Areas:  

Metabolic Disease Inflammation/Immunology

NLRP3/URAT1-IN-1 is an orally active double inhibitor of NLRP3 and URAT1 (IC50 = 3.81 μM). NLRP3/URAT1-IN-1 inhibits IL-1β release in LPS (HY-D1056) and ATP-stimulated mouse bone marrow-derived macrophages (BMDMs), with an IC50 of 2.61 μM. NLRP3/URAT1-IN-1 reduces serum uric acid (SUA) and alleviates liver/kidney damage in mice with acute hyperuricemia (HUA). NLRP3/URAT1-IN-1can be used for the study of gout and hyperuricemia .
Cristacarpin
Cristacarpin
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Cat. No.: HY-N3642
CAS No.: 74515-47-2
Synonyms: Erythrabyssin I; Erythrabissin I
Category:  

Leguminosae Erythrina suberosa Roxb. Plants

Target:  

Others

Cristacarpin can be extracted from the stem bark of Erythrina suberosa, promotes endoplasmic reticulum (ER) stress, leading to sublethal reactive oxygen species (ROS) production and ultimately cell death through senescence .
Abyssinone V
Abyssinone V
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Cat. No.: HY-N8265
CAS No.: 77263-11-7
Category:  

Flavonoids Leguminosae Erythrina melanacantha Taub. ex Harms Flavonones Plants

Target:  

HSV DNA/RNA Synthesis ATP Synthase

Abyssinone V is a prenylated flavonoid with predicted anti-viral activity. Abyssinone V can be isolated from the stem bark of Erythrina melanacantha. Abyssinone V possesses good pharmacodynamics properties. Abyssinone V is predicted to be antivirals including anti-herpes (HSV) agent, with mechanisms comprising inhibition of polymerase, ATPase and membrane integrity .
Erythrina Cristagalli Lectin
Erythrina Cristagalli Lectin
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Cat. No.: HY-NP066
Synonyms: ECL
Erythrina Cristagalli Lectin (ECL) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Erythrina Cristagalli Lectin (ECL) is a biological material or organic compound that can be used in life science research .
Erythrina Cristagalli Lectin (Biotinylated)
Erythrina Cristagalli Lectin (Biotinylated)
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Cat. No.: HY-NP0177
Synonyms: ECL (Biotinylated)
Erythrina Cristagalli Lectin (ECL) Biotinylated is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Erythrina Cristagalli Lectin (ECL) Biotinylated is a biological material or organic compound that can be used in life science research .
Erythrina Cristagalli Lectin (Fluorescein)
Erythrina Cristagalli Lectin (Fluorescein)
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Cat. No.: HY-NP099
Synonyms: ECL (Fluorescein)
Erythrina Cristagalli Lectin (ECL) Fluorescein is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Erythrina Cristagalli Lectin (ECL) Fluorescein is a biological material or organic compound that can be used in life science research .
Neocyclomorusin
Neocyclomorusin
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Cat. No.: HY-N8272
CAS No.: 62596-35-4
Category:  

Flavonoids Leguminosae Plants Other Flavonoids Erythrina sigmoidea Hua

Target:  

Others

Neocyclomorusin (compound 6) is a flavonoid. Neocyclomorusin can be isolated from Erythrina sigmoidea. Neocyclomorusin inhibits the CCRF-CEM cell line with an IC50 value of 59.02 μM .
Erythrodiol diacetate
Erythrodiol diacetate
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Cat. No.: HY-N12160
CAS No.: 1896-77-1
Category:  

Erythrina eriotriocha Leguminosae Plants

Target:  

Others

Erythrodiol diacetate (Compound 4) is a triterpenoid compound derived from Erythrina eriotriocha stem bark .
Erythrinasinate B
Erythrinasinate B
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Cat. No.: HY-N3160
CAS No.: 101959-37-9
Synonyms: Octacosyl (E)-ferulate
Category:  

Monophenols Phenols Plants Erythrina caffra Thunb. Fabaceae

Target:  

Parasite

Octacosyl (E)-ferulate (Erythrinasinate B) (Compound 1) is an antiplasmodial compound. Octacosyl (E)-ferulate can be isolated from Erythrina .
Erythrivarone A
Erythrivarone A
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Cat. No.: HY-N3743
CAS No.: 63807-90-9
Synonyms: Dihydroalpinumisoflavone
Category:  

Flavonoids Leguminosae Plants Erythrina variegata Linn. Isoflavones

Target:  

Others

Erythrivarone A is an isoflavone that can be isolated from the stem bark of Erythrina variegate .
Piscerygenin
Piscerygenin
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Cat. No.: HY-N10977
CAS No.: 67978-85-2
Category:  

Piscidia erythrina L. Xanthones Leguminosae Phenols Plants

Target:  

Others

Piscerygenin (compound 4), an isoflavonoid, is a nature product that could be isolated from the root bark of Piscidia erythrina .
Assay Types